The house fire happened in Earles Chapel right outside of Jacksonville.
Fire officials say the house was owned by an elderly man and woman who had been eating lunch when the fire started.
With the execption of a purse, which the woman grabbed before leaving the burning house, all of their belongings were lost in the blaze.
An investigation as to how exactly the fire started is underway.
Jacksonville Fire Department officials confirm with Fox51 there is a structure on fire in Jacksonville off of Highway 79 West.
Crews are at the scene of the blaze trying to put it out.
Fox51 will have more information when it becomes available.