(CNN) — A deadly winter storm stretching from Southern California to Texas threatened to wreck Thanksgiving week travel plans all the way to the Atlantic.
At least five people have lost their lives in traffic crashes blamed on the storm system since late last week.
Three died when nine tractor-trailer trucks and two cars slid into each other on icy Interstate 40 in northwest Texas late Friday, according to Texas State Trooper Chris Ray.
The dead included passengers in each of the cars and one of the truck drivers, who was struck by one of the cars after he left his cab, Ray said. Several other people were critically injured and taken to hospitals 35 miles away in Amarillo, Texas, Ray said..
At least 20 people were taken to local hospitals from collisions within three miles of the fatal pileup, according to Oldham County, Texas, Sheriff David Medlin.
"We have about 4 inches of snow on the ground," Medlin told CNN on Sunday. "Road conditions are still dangerous and people should drive cautiously and avoid roads unless absolutely needed."
Ice is blamed for causing Willie Nelson's band bus to spin out of control and crash into a bridge pillar on Interstate 30 near Sulfur Springs, Texas, early Saturday. Three of the five members of Nelson's band were hurt, according to police and the band. Nelson was not on board.
Flood threat in Arizona
Lingering rain prolonged the flood threat in Arizona, the weather service said. Friday's 1.6 inches of rain in Phoenix made it the second wettest November day ever recorded in the desert city. Lighter amounts were falling Saturday, but drainage areas already were full.
In New Mexico and West Texas, snow and ice covered Interstate 10. The highway was open through Texas, but officials urged caution, especially on bridges.
New Mexico could see up to 8 inches of snow accumulating through Monday.
Storm will reach Carolinas by Monday
On Sunday, the forecast for northern Texas and parts of Oklahoma called for rain and sleet, and some spots are expected to get up to 4 inches of snow. Rain and sleet will extend through Dallas and into northern Louisiana.
Rain is expected to stretch from Texas to Georgia on Monday and to the Carolinas on Monday night, with sleet and snow in northern parts of that swath.
By Tuesday, the rain will reach the mid-Atlantic states and parts of the Northeast.
Travel delays next week in Northeast
Rain, wind and possibly snow will cause travel delays beginning as early as Tuesday in the East, said CNN meteorologist Melissa Le Fevre.
"We are going to see delays," Le Fevre said. "We're just waiting to see if the impacts are going to be severe or just annoying."
The deciding factor will be whether a low-pressure system moving north out of the Gulf of Mexico travels inland or close to the East Coast, she said.
According to AAA projections, 43.4 million Americans will travel 50 miles or more from home during the Thanksgiving holiday weekend this year.